Tag "frontiers of science"

Renewable energy and labour productivity do not always contribute to environmental sustainability. Technological innovation is the only factor that consistently has a positive effect. This is the conclusion reached by an international team of researchers, including Natalia Veselitskaya, Leading Research Fellow at the HSE ISSEK Foresight Centre. The study has been published in Sustainable Development.

Scientists at HSE University have discovered that in preeclampsia—one of the most severe complications of pregnancy—the placenta remodels its lipid metabolism, reducing its own cholesterol synthesis while increasing cholesterol transfer to the foetus. This compensatory mechanism helps sustain foetal nutrition but accelerates placental deterioration and may lead to preterm birth. The study findings have been published in Frontiers in Molecular Biosciences.

HSE researchers evaluated the accuracy of technology forecasts in the transportation sector over the past 50 years and found that the average accuracy rate does not exceed 25%, with the lowest accuracy observed in aviation and rail transport. According to the scientists, this is due to limitations of the forecasting method and the inherent complexities of the sector. The study findings have been published in Technological Forecasting and Social Change.

A team of scientists, including researchers from HSE University, has proposed a method for assessing stress resilience using physiological markers derived from wearable devices and saliva samples. The participants who adapted better to stress showed higher heart rate variability, higher zinc concentrations in saliva, and lower potassium levels.  The findings were published in the Journal of Molecular Neuroscience.

HSE researchers have found that the likelihood of quitting smoking rises with increasing financial struggles. While low levels of financial difficulties do not affect smoking behaviour, moderate financial stress can increase the probability of quitting by 13% to 21%. Responses to high financial stress differ by gender: men are almost 1.5 times more likely to give up cigarettes than under normal conditions, whereas no significant effect is observed on women’s decisions to quit smoking. These conclusions are based on data from the Russia Longitudinal Monitoring Survey (RLMS-HSE) for 2000–2023 and have been published in Monitoring of Public Opinion: Economic and Social Changes. 

Researchers from the HSE Center for Language and Brain and the Mental Health Research Centre have proposed a new method of linguistic analysis that enables the distinction between normal and pathological ageing. Using this approach, they showed that patterns in patients’ word choices during verbal fluency tests allow clinicians to more accurately differentiate clinically significant impairments from subjective memory complaints. Incorporating this type of analysis into clinical practice could improve the accuracy of early dementia diagnosis. The results have been published in Applied Neuropsychology: Adult.

Researchers from the HSE Center for Language and Brain used magnetoencephalography to study how the brains of adults and children respond to words during reading. They showed that in children the brain takes longer to process words that are frequently used in everyday speech, while rare words and pseudowords are processed in the same way—slowly and in parts. With age, the system is reorganised: high-frequency words shift to a fast route, whereas new letter combinations are still analysed slowly. The study was published in the journal Psychophysiology.

Scientists at HSE University have investigated the effect of parks on the cognitive and emotional resources of city dwellers. The researchers compared brain electrical activity in 30 participants while they watched videos of walks through parks and along busy highways. The results showed that green urban environments with trees produce a consistent effect across individuals, helping the brain calm down and relax. By contrast, walks along busy streets were found to be distracting. The findings have been published in Scientific Reports.

Scientists at HSE MIEM, in collaboration with colleagues from China, have developed a method to improve the durability of perovskite solar cells by addressing iodine loss from the material. The researchers introduced quaternary ammonium molecules into the perovskite structure; these molecules form strong electrostatic pairs with iodine ions, effectively anchoring them within the crystal lattice. As a result, the solar cells retain more than 92% of their power after a thousand hours of operation at 85°C. The study has been published in Advanced Energy Materials.

An international team, including researchers from HSE University, has created the first comprehensive map of quadruplexes—unstable DNA structures involved in gene regulation. For the first time, scientists have shown that these structures function in pairs: one is located in a DNA region that initiates gene transcription, while the other lies in a nearby region that enhances this process. In healthy tissues, quadruplexes regulate tissue-specific genes, whereas in cancerous tissues they influence genes responsible for cell growth and division. These findings may contribute to the development of new anticancer drugs that target quadruplexes. The study has been published in Nucleic Acids Research.