HSE Development Programme until 2030

Researchers from the International Laboratory of Microphysiological Systems at HSE University's Faculty of Biology and Biotechnology are developing methods to reduce tumour cell resistance to drugs and to create more effective, personalised cancer treatments. In this interview with the HSE News Service, Diana Maltseva, Head of the Laboratory, talks about their work.

Why we make irrational decisions, how the brain responds to fakes, and whether neural networks are capable of thinking—these were the topics discussed by early-career scientists of HSE University during the NAUKA 0+ science festival. The event brought together students and experts from various fields, united by a common goal—to deepen their understanding of the human brain and cognitive technologies.

In September 2025, the HSE Faculty of Urban and Regional Development (FURD) hosted a delegation of leading scholars and urban development experts from China. Two seminars were held at the Shukhov Lab with the participation of Chinese colleagues: the first focused on green infrastructure, while the second explored the theme of dynamic urbanism. In addition, a meeting between the Chinese delegation and representatives of FURD took place at the university’s main building on Pokrovsky Bulvar. The participants discussed opportunities for expanding cooperation between universities and research centres.

Researchers from the HSE Centre for Language and Brain have developed a tool for accurately assessing reading skills in adults with reading impairments. It can be used, for instance, before and after sessions with a language therapist. The tool includes two texts that differ in content but are equal in complexity: participants were observed to read them at the same speed, make a similar number of errors, and understand the content to the same degree. Such parallel texts will enable more accurate diagnosis of dyslexia and better monitoring of the effectiveness of interventions aimed at addressing it. The paper has been published in Educational Studies.

The final stage of the 5th International Olympiad on Financial Security took place at the Siberian Federal University in Krasnoyarsk from September 29 to October 3. The event brought together 600 students from schools and universities from 40 different countries. The Higher School of Economics was represented at all three levels of the Olympiad: competition, expert, and career guidance.

As part of the Rediscovering Russia student expedition programme, HSE University organised a research trip under the framework of the School for Young Humanities Scholars to the New Chersonesos museum and church complex in Sevastopol. The results of this expedition will form the basis for proposals on educational projects aimed at shaping young people’s historical memory of the role of Chersonesos, Crimea, and the Byzantine legacy in the history of Russian culture and statehood.

For the first time in Russia, a team of scientists and clinicians has conducted a large-scale genetic study of patients with pulmonary arterial hypertension. The team, which included researchers from the International Laboratory of Bioinformatics at the HSE Faculty of Computer Science, analysed the genomes of over a hundred patients and found that approximately one in ten carried pathogenic mutations in the BMPR2 gene, which is responsible for vascular growth. Three of these mutations were described for the first time. The study has been published in Respiratory Research.

On September 17–20, 2025, the First Caucasus School on Experimental Research and Cognitive Sciences took place at the Gornaya Legenda venue of Adyghe State University (ASU). The event was organised by the ASU Experimental Linguistics Laboratory, the HSE Centre for Language and Brain, and the HSE Centre for Sociocultural and Ethnolinguistic Studies. The school brought together over 50 participants—students, doctoral candidates, and early-career researchers from across Russia, along with lecturers and speakers from France, Serbia, China, Turkey, Kazakhstan, and Uzbekistan.

An international team of scientists, including researchers from the HSE Centre for Language and Brain, has for the first time studied the connectivity between the brain's sensorimotor and cognitive control networks in children with autism. Using fMRI data, the researchers found that connections within the cognitive control network (responsible for attention and inhibitory control) are weakened, while connections between this network and the sensorimotor network (responsible for movement and sensory processing) are, by contrast, excessively strong. These features manifest as difficulties in social interaction and behavioural regulation in children. The study has been published in Brain Imaging and Behavior.

Researchers at HSE University have developed a new methodological approach to studying motor planning and execution. By using 3D-printed objects and an infrared tracking system, they demonstrated that the brain initiates the planning process even before movement begins. This approach may eventually aid in the assessment and treatment of patients with neurodegenerative diseases such as Parkinson’s. The paper has been published in Frontiers in Human Neuroscience.